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Anti-ALK (C1156Y) Mouse Monoclonal Antibody
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TD-262261
TD-262262
- Catalog： TD-26226
- Clonality： mAb
- Application： ELISA, WB, IF, IHC
- Synonyms： ALK(C1156Y)
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规格：
100ul
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价格：
¥4800
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Anti-ALK (C1156Y) Mouse Monoclonal Antibody
| Cat. #: TD-26226 | |
| Gene Symbol: ALK, CD246, NBLST3 | |
| Description: Anti-ALK(C1156Y) Mouse Monoclonal Antibody | |
| Background: Anaplastic lymphoma kinase (ALK) also known as CD246 (cluster of differentiation 246) is a tyrosine kinase receptor that plays an important role in the development of the brain and nervous systems. Deficiencies in ALK, which most commonly as a fusion with other genes, are indicated in cancers. | |
| Immunogen: A synthetic peptide from the internal region of ALK which includes the mutation of C1156Y, human origin. | |
| Applications: ELISA, WB, IF, IHC | |
| Recommended Dilutions: ELISA: 1:1000-1:5000、WB: 1:500-1:2000、IF: 1:50-1:100、IHC: 1:50-1:100 | |
| Concentration: 1 mg/ml | |
| Host Species: Mouse | |
| Format: Liquid | |
| Clonality: Monoclonal | |
| Isotype: | |
| Purity: Purified from ascites | |
| Preservative: No | |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol | |
| Species Reactivity: Recognizes C1156Y mutant, but not wild type ALK of vertebrates. | |
| Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing | |
|
Western blot: |
Western blot analysis of recombinant ALK(C1156Y) and wild type proteins. Purified His-tagged ALK(C1156Y) protein (lane 2) and corresponding wild type protein (lane 1) were blotted with Anti-ALK(C1156Y) monoclonal antibody (Cat. #TD-26226). |
|
Immunofluorescence: |
Immunofluorescence of cells expressing ALK proteins with Anti-ALK(C1156Y) antibody. HEK293T cells were transfected with pCDNA3-GFP-ALK (WT) plasmid (left column) or pCDNA3-GFP-ALK(C1156Y) plasmid (right column), then fixed and stained with Anti-ALK(C1156Y) monoclonal antibody (Cat. #TD-26226). |