| Product Name |
NF-kB p65 mouse monoclonal antibody |
| Cat.# |
TD-AB0026 |
| Package |
25 μl/100 μl/200 μl |
| Storage |
PBS with 0.1% sodium azide and 50% glycerol, pH 7.2 |
| Product Imformation |
| Description |
NF-kB p65 Monoclonal Antibody |
| Applications |
WB |
| Immunogen |
Recombinant Protein |
| Reactivity |
Human, Mouse, Rat |
| Host species |
Mouse |
| Ig class |
IgG1 |
| Purity |
Protein A/G Affinity Purification |
| Target information |
| Symbol |
|
| Synonyms |
RELA; NFKB3; Transcription factor p65; Nuclear factor NF-kappa-B p65 subunit |
| |
|
| Target Background |
| NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for RELA |