TD-AF687014

ELISA

Rabbit

IgG

Polyclonal

Eculizumab

Rabbit polyclonal to Soliris.

The product is specific for Eculizumab. This antibody serves as an excellent positive control for Eculizumab immunogenicity (ADA) assays.

Please contact with the lab for this information.

Purified by antigen affinity column.

CAS: 219685-50-4

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

ELISA　|　IHC　|　WB

1:5000-1:20000　|　1:50-1:500　|　1:500-1:2000

The product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles.

Eculizumab with trade name Soliris, is an FDA-approved drug to treat paroxysmal nocturnal hemoglobinuria (PNH), atypical hemolytic uremic syndrome (aHUS), and neuromyelitis optica. Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5. Eculizumab specifically binds to the terminal complement component 5, or C5. Binding to this protein prevents the activation of a complement terminal complex, which is used to treat a number of autoimmune conditions.• Induction Immunosuppression in High-risk Kidney Transplant Recipients., PMID:27041548• Acute Rejection Following Kidney Transplantation: State-of-the-Art and Future Perspectives., PMID:32520680• The impact of terminal complement blockade on the efficacy of induction with polyclonal rabbit antithymocyte globulin in living donor renal allografts., PMID:22813834

For research use only.