抗体
试剂盒
多肽
探针
蛋白
组织芯片
产品中心
Product Center
CD160
All
ELISA
FCM
- Catalog： TD-32322
- Clonality： mAb
- Application： FCM
- Synonyms： NK1; BY55; NK28
-
规格：
100ul 50ul
-
价格：
¥2180
定制服务咨询
Mouse Monoclonal Antibody to CD160
| Description | |
| CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules. | |
| Specification | |
| Aliases | NK1; BY55; NK28 |
| Entrez GeneID | 11126 |
| Swissprot | O95971 |
| clone | 1D4A4 |
| WB Predicted band size | 19.8kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human CD160 (AA: 25-155) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
| Application | |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
| Product Image | |
|
Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
|
Flow cytometric analysis of Jurkat cells using CD160 mouse mAb (green) and negative control (red).
|